Chronic fatigue is characterized by which of the following?

Chronic fatigue is best characterized by constant fatigue, stiffness, and lack of coordination. This condition is often persistent and does not improve with rest. Individuals experiencing chronic fatigue may find that their symptoms interfere with their daily activities and overall quality of life. The fatigue is not merely a result of sleep disruption or temporary exertion, but rather a prolonged state that can include additional symptoms such as muscle pain, cognitive difficulties, and sleep disturbances.

In contrast, the other options describe different states of fatigue or temporary conditions rather than chronic fatigue syndrome. Short-term sleep disruption and irritability, for example, may be symptoms related to sleep disorders or temporary stress rather than the sustained and holistic impact of chronic fatigue. Temporary exhaustion from high activity levels typically resolves with adequate rest and is not indicative of the persistent nature of chronic fatigue. Feeling tired after a long day at work is a common experience that is typically linked to daily fatigue, which contrasts with the enduring and profound exhaustion associated with chronic fatigue.